1,3-二甲基-1,3-二氢-2H-吲哚-2-酮合成路线 （共 38 条）
反应条件
1.1: sodium nitrite; dipotassium peroxodisulfate / acetonitrile / 16 h / 120 °C / |Sealed tube
2.1: sodium hydroxide; disodium hydrogenphosphate / methanol / 1 h
2.2: 1 h / 20 °C
View Scheme
参考文献
Li, Ya-Min; Wei, Xiao-Hong; Li, Xi-An; Yang, Shang-Dong
Chemical Communications, 2013 , vol. 49, # 99 p. 11701 - 11703
反应条件
1.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; caesium carbonate / tetrahydrofuran; water / 16 h / |Reflux
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h
2.2: 0.5 h
3.1: tri-ruthenium(0)dodecacarbonyl; tetra-(n-butyl)ammonium iodide / toluene; dimethyl sulfoxide / 12.08 h / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h
1.2: 0.5 h
2.1: tri-ruthenium(0)dodecacarbonyl; tetra-(n-butyl)ammonium iodide / toluene; dimethyl sulfoxide / 12.08 h / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131
反应条件
1: potassium tert-butylate; copper (II) acetate monohydrate / N,N-dimethyl-formamide / 1 h / 110 °C
2: trifluoroacetic acid; methoxybenzene / neat (no solvent) / 20 °C
View Scheme
参考文献
Pugh, David S.; Taylor, Richard J.K.
Organic Syntheses, 2012 , vol. 89, p. 438 - 449
反应条件
Unter Stickstoff und anschliessend mit Methyljodid;
参考文献
Wenkert et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 797,798
反应条件
sodium hydride; benzene
anschliessend mit Methyljodid;
参考文献
Wenkert et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 797,798
反应条件
ethanol; sodium ethanolate
参考文献
Julian et al.
Journal of the American Chemical Society, 1934 , vol. 56, p. 1797,1800
反应条件
oxygen; Co(Salpr) in methanol
24 h;
参考文献
Inada, Akira; Morita, Yutaka
Heterocycles, 1982 , vol. 19, # 11 p. 2139 - 2142
