8,9-二氢-6H-吡啶并[2,1-b]喹唑啉-11(7h)-酮合成路线 （共 42 条）
反应条件
1: 98 percent / AcOH; AcONa / H2O / -5 - 5 °C / pH 4 2: 82 percent / H-mordenite; AcOH / 5 h / Heating View Scheme
参考文献
Koekoesi, Jozsef; Hermecz, Istvan; Szasz, Gyoergy; Meszaros, Zoltan
Tetrahedron Letters, 1981 , vol. 22, # 48 p. 4861 - 4862
参考文献
Koekoesi, Jozsef; Hermecz, Istvan; Szasz, Gyoergy; Meszaros, Zoltan
Tetrahedron Letters, 1981 , vol. 22, # 48 p. 4861 - 4862
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
T=20°C; 3 h;
参考文献
Fang, Jie; Zhou, Jianguang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 12 p. 2389 - 2391
反应条件
triphenylphosphine-impregnated polystyrene in dichloromethane
T=20°C; 4 h;
参考文献
Kamal, Ahmed; Devaiah; Shankaraiah; Laxma Reddy
Synlett, 2006 , # 16 p. 2609 - 2612
反应条件
pyridine; triphenylphosphine
T=220°C; 0.166667 h; microwave irradiation;
参考文献
Liu, Ji-Feng; Ye, Ping; Sprague, Kevin; Sargent, Katie; Yohannes, Daniel; Baldino, Carmen M.; Wilson, Christopher J.; Ng, Shi-Chung
Organic Letters, 2005 , vol. 7, # 15 p. 3363 - 3366
反应条件
1: piperidin-2-one With hydrogenchloride in chloroform
2: With trichlorophosphate
T=40°C; 2 h;
3: 2-amino-benzoic acid methyl ester in tetrahydrofuran
T=20°C; 12 h;
参考文献
Lee, Eung Seok; Park, Jae-Gyu; Jahng, Yurngdong
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1883 - 1886
反应条件
potassium permanganate in acetone
2 h; Reflux;
参考文献
Richers, Matthew T.; Deb, Indubhusan; Platonova, Alena Yu.; Zhang, Chen; Seidel, Daniel
Synthesis (Germany), 2013 , vol. 45, # 13 art. no. SS-2013-C0210-FA, p. 1730 - 1748
反应条件
Fe(F20TPP)Cl in 1,2-dichloro-ethane
24 h; Molecular sieveRefluxInert atmosphere;
参考文献
Liu, Yungen; Wei, Jinhu; Che, Chi-Ming
Chemical Communications, 2010 , vol. 46, # 37 p. 6926 - 6928
反应条件
in benzene
12 h; Cooling;
参考文献
Nepali, Kunal; Ojha, Ritu; Singh, Aninder; Budhiraja, Abhishek; Bedi, Preet Mohinder Singh; Dhar, Kanaya Lal
Letters in Drug Design and Discovery, 2013 , vol. 10, # 6 p. 522 - 528
反应条件
[{(η5-C5Me5)IrCl}2(μ-Cl)2]; trifluorormethanesulfonic acid in anhydrous xylene
36 h; Inert atmosphereReflux;
参考文献
Fang, Jie; Zhou, Jianguang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 12 p. 2389 - 2391
