sodium hydroxide; bromine in 1,4-dioxane; water T=60°C; Oxidation; 4 h;

1.1: H2 / 10 percent Pd/C / ethyl acetate / 72 h / 2068.59 - 2327.17 Torr 1.2: 30 g / AlCl3 / CH2Cl2 / 2.5 h / 0 - 20 °C 2.1: 100 percent / Br2; NaOH / H2O; dioxane / 4 h / 60 °C View Scheme