(2E)-3-(4-吡啶基)丙烯腈合成路线 （共 4 条）
参考文献
Strell; Kopp
Chemische Berichte, 1958 , vol. 91, p. 1621,1629
反应条件
ammonium formate; palladium 10 on activated carbon in ethanol; water 2.5 h; Heating / reflux;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1424336 A1, 2004 ;
Location in patent: Page 245 ;
反应条件
1: cyanomethyl-phosphonic acid diethyl ester With sodium hydride in tetrahydrofuran
1 h;
2: pyridine-2-carbaldehyde in tetrahydrofuran
T=0 - 20°C; 3 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1424336 A1, 2004 ;
Location in patent: Page 245-246 ;
反应条件
copper
T=175 - 180°C; stereoisomer(ic) of mp: 71 degree;
参考文献
Strell; Kopp
Chemische Berichte, 1958 , vol. 91, p. 1621,1629
