(7CI,8CI,9CI)-吡啶并[1,2-a]苯并咪唑合成路线 （共 34 条）
反应条件
Iron (III) nitrate nonahydrate; oxygen; copper diacetate; 2,2,2-trimethylacetic acid in N,N-dimethyl-formamide
T=130°C; 18 h;
参考文献
Wang, Honggen; Wang, Yong; Peng, Changlan; Zhang, Jiancun; Zhu, Qiang
Journal of the American Chemical Society, 2010 , vol. 132, # 38 p. 13217 - 13219
反应条件
copper(l) iodide; 1,10-phenanthroline; caesium carbonate in anhydrous xylene
T=120°C; Ullmann type reaction; 24 h; Inert atmosphere;
参考文献
Wu, Zhiqing; Huang, Qing; Zhou, Xiangge; Yu, Lintao; Li, Zhengkai; Wu, Di
European Journal of Organic Chemistry, 2011 , # 27 p. 5242 - 5245
反应条件
hexafluoroisopropyl alcohol; PhI(OPiv)2
T=25°C; 7 h;
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
反应条件
1: 80 percent / 3.5 h / 150 °C
2: 60 percent / NaOH / 2-methyl-propan-2-ol; H2O / 5 h / Irradiation
View Scheme
参考文献
Baklanov, M. V.; Frolov, A. N.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 3.2 p. 550 - 559
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 3 p. 638 - 649
反应条件
1: Na2CO3; ethanol
2: acetic acid; HBr
3: palladium/charcoal / 300 °C
View Scheme
参考文献
Campbell; McCall
Journal of the Chemical Society, 1951 , p. 2411,2415
反应条件
T=700°C; Elimination; Cyclization; P=0.01 Torr;
参考文献
Janowski, Wit K.; Prager, Rolf H.; Smith, Jason A.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 19 p. 3212 - 3216
反应条件
1: 94 percent / t-BuONa; 1,1'-bis(diphenylphosphino)ferrocine / Pd2(dba)3 / toluene / 14 h / 100 °C
2: 59 percent / Na2CO3 / Pd(OAc)2 / dimethylformamide / Heating
View Scheme
参考文献
Iwaki, Takehiko; Yasuhara, Akito; Sakamoto, Takao
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 11 p. 1505 - 1510
反应条件
1: tetrahydrofuran / -30 - 50 °C
2: PhI(OPiv)2 / 2.5 h / 25 °C
View Scheme
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
反应条件
PhI(OPiv)2
T=25°C; 2.5 h; Overall yield = 93 percent;
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
反应条件
PhI(OPiv)2
T=25°C; 2.5 h; Overall yield = 94 percent;
参考文献
Liang, Dongdong; He, Yimiao; Liu, Lanying; Zhu, Qiang
Organic Letters, 2013 , vol. 15, # 13 p. 3476 - 3479
