4H-[1,3]噻嗪并[3,2-a]苯并咪唑合成路线 （共 6 条）
反应条件
bromine; sodium acetate in N,N-dimethyl-formamide
T=80°C; 5 h;
参考文献
Korotkikh, N. I.; Raenko, G. F.; Shvaika, O. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 3 p. 359 - 363
Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 3 p. 410 - 415
反应条件
potassium hydroxide in ethanol
T=78°C; regiospecific reaction;
参考文献
Novikov; Danilkina; Balova
Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 6 p. 758 - 766
反应条件
1: 57 percent / bromine / acetic acid / 20 °C
2: 68 percent / H2O; propan-2-ol / 15 h / Heating
3: 89 percent / sodium acetate / H2O; CHCl3 / 1 h
4: KOH / methanol / 6 h / Heating
View Scheme
参考文献
Korotkikh; Raenko; Aslanov
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 4 p. 610 - 618
反应条件
bromine; sodium acetate in N,N-dimethyl-formamide
T=80°C; 5 h; Title compound not separated from byproducts;
参考文献
Korotkikh, N. I.; Raenko, G. F.; Shvaika, O. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 3 p. 359 - 363
Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 3 p. 410 - 415
反应条件
sodium hydroxide in methanol
6 h; Heating;
参考文献
Korotkikh, N. I.; Raenko, G. F.; Shvaika, O. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1995 , vol. 31, # 3 p. 359 - 363
Khimiya Geterotsiklicheskikh Soedinenii, 1995 , # 3 p. 410 - 415
反应条件
potassium hydroxide in ethanol
1 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Klyuev, N. A.; Krasovskii, A. N.; Sheinkman, A. K.; Krasovskii, I. A.; Zhil'nikov, V. G.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 1555 - 1561
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 8 p. 1739 - 1746
