2,3-二(苯基)丁-2-烯二腈合成路线 （共 24 条）
反应条件
sodium azide in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=-10°C; Yield given;
参考文献
Levi, Hugo A.; Landen, George L.; McMills, Mark; Albiziati, Kim; Moore, Harold W.
Tetrahedron Letters, 1982 , vol. 23, # 3 p. 299 - 302
反应条件
n-butyllithium; (Pentachlorophenyl)lithium in tetrahydrofuran; diethyl ether
1.) -70 deg C, 2 h, 2.) -70 deg C, 2 h; r.t., 12 h;
参考文献
Refat, Hala Mohammed; Waggenspack, John; Dutt, Mahesh; Zhang, Hongming; Fadda, A. A.; Biehl, Ed
Journal of Organic Chemistry, 1995 , vol. 60, # 7 p. 1985 - 1989
反应条件
n-butyllithium in tetrahydrofuran; diethyl ether
1.) -70 deg C, 2 h, 2.) -70 deg C, 2 h; r.t., 12 h;
参考文献
Refat, Hala Mohammed; Waggenspack, John; Dutt, Mahesh; Zhang, Hongming; Fadda, A. A.; Biehl, Ed
Journal of Organic Chemistry, 1995 , vol. 60, # 7 p. 1985 - 1989
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=-60 - 20°C; 3 h;
参考文献
Araki, Shuki; Yokoi, Keisaku; Sato, Ryosuke; Hirashita, Tsunehisa; Setsune, Jun-Ichiro
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 164 - 171
反应条件
sodium azide in dimethyl sulfoxide
T=25°C; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Tanaka, Ryuichi; Yamabe, Kuniaki
Journal of the Chemical Society, Chemical Communications, 1983 , # 7 p. 329 - 330
反应条件
sodium hydroxide in ethylene glycol dimethyl ether
T=0 - 5°C; 0.166667 h; Title compound not separated from byproducts.;
参考文献
Jonczyk; Gadaj
Polish Journal of Chemistry, 2007 , vol. 81, # 9 p. 1595 - 1610
反应条件
sodium azide in dimethyl sulfoxide
T=25°C; Further byproducts given. Yields of byproduct given;
参考文献
Tanaka, Ryuichi; Yamabe, Kuniaki
Journal of the Chemical Society, Chemical Communications, 1983 , # 7 p. 329 - 330
反应条件
sodium azide in dimethyl sulfoxide
T=25°C; Further byproducts given. Yields of byproduct given;
参考文献
Tanaka, Ryuichi; Yamabe, Kuniaki
Journal of the Chemical Society, Chemical Communications, 1983 , # 7 p. 329 - 330
反应条件
n-butyllithium; 1-bromo-2,3,4,5,6-pentafluorobenzene
1.) THF, -70 deg C, 2 h, 2.) Et2O,-70 deg C to r.t.; Yields of byproduct given;
参考文献
Refat, Hala Mohammed; Faddo, Ahmed A.; Biehl, Ed
Journal of Fluorine Chemistry, 1996 , vol. 76, # 1 p. 99 - 103
反应条件
1: 82 percent / LiCN / tetrahydrofuran / Ambient temperature
2: 76 percent / n-BuLi, TMEDA / tetrahydrofuran; hexane / -78 °C
View Scheme
参考文献
Kurihara, Takushi; Santo, Kazunori; Harusawa, Shinya; Yoneda, Ryuji
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 12 p. 4777 - 4788
