(1R,2R)-2-{[(叔丁氧基)羰基]氨基}环戊烷-1-羧酸合成路线 （共 12 条）
反应条件
lithium hydroxide; dihydrogen peroxide in methanol T=5°C; Hydrolysis; 20 h;
参考文献
Appella, Daniel H.; Christianson, Laurie A.; Klein, Daniel A.; Richards, Michele R.; Powell, Douglas R.; Gellman, Samuel H.
Journal of the American Chemical Society, 1999 , vol. 121, # 33 p. 7574 - 7581
反应条件
1: AcOH / ethanol 2: NaCNBH3 3: LiOH 4: H2 / Pd/C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
反应条件
1: LiOH 2: H2 / Pd/C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 46 p. 15067 - 15073
反应条件
1: 18 percent / tetrahydrofuran / 48 h 2: 67 percent / aq. LiOH; H2O2 / methanol / 20 h / 5 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 33 p. 7574 - 7581
反应条件
1: HN3; Ph3P; diethyl azodicarboxylate / benzene; ethanol / 8 h / 10 - 20 °C 2: Ph3P; H2O / tetrahydrofuran / 18 h 3: 18 percent / tetrahydrofuran / 48 h 4: 67 percent / aq. LiOH; H2O2 / methanol / 20 h / 5 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 33 p. 7574 - 7581
反应条件
sodium hydroxide in 1,4-dioxane; water 1 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 98 percent / SnCl4 / CH2Cl2 / 24 h / Ambient temperature 2: 88 percent / NaOH / dioxane; H2O / 2 h / Ambient temperature 3: 73 percent / diphenylphosphorylazide, Et3N / 18 h / 80 °C 4: 88 percent / Raney-Nickel / methanol / 4 h / Heating 5: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 73 percent / diphenylphosphorylazide, Et3N / 18 h / 80 °C 2: 88 percent / Raney-Nickel / methanol / 4 h / Heating 3: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 88 percent / NaOH / dioxane; H2O / 2 h / Ambient temperature 2: 73 percent / diphenylphosphorylazide, Et3N / 18 h / 80 °C 3: 88 percent / Raney-Nickel / methanol / 4 h / Heating 4: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
反应条件
1: 88 percent / Raney-Nickel / methanol / 4 h / Heating 2: NaOH / dioxane; H2O / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 53, # 23 p. 7975 - 7984
