反应条件
1: 87.5 mg / 1-hydroxybenzotriazole; triethylamine; 1-(3-diethylaminopropyl)-3-ethylcarbodiimide hydrochloride / tetrahydrofuran; CH2Cl2 / 0 - 20 °C
2: hydrogen / Pd(OH)2 on carbon / ethyl acetate / 2 h / 20 °C
3: 89 percent / 4-(dimethylamino)pyridine; 1,3-diisopropylcarbodiimide / CH2Cl2 / 18 h / 20 °C
4: CH2Cl2 / 0 - 20 °C
5: 31.0 mg / NaHCO3; diphenyl phosphorazidate / dimethylformamide / 72 h / 0 °C
6: 55 percent / dimethyldioxirane / CH2Cl2; acetone / -30 - 20 °C
View Scheme
参考文献
White, James D.; Hong, Jian; Robarge, Lonnie A.
Journal of Organic Chemistry, 1999 , vol. 64, # 17 p. 6206 - 6216
