4-羟基-5-甲氧基-2-硝基苯甲醛合成路线 （共 18 条）
反应条件
1: water; nitric acid / 0 °C 2: concentrated sulfuric acid / 50 - 60 °C View Scheme
参考文献
Nair; Robinson
Journal of the Chemical Society, 1932 , p. 1236,1238
反应条件
T=2 - 6°C; Nitrierung,und folgende Verseifung mit Kalilauge;
参考文献
Raiford; Stoesser
Journal of the American Chemical Society, 1928 , vol. 50, p. 2561
反应条件
1: 90 percent / K2CO3 / dimethylformamide / 2 h / 100 °C 2: FeSO4*7H2O, 25 percent NH4OH / 0.08 h / 100 °C View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
potassium carbonate in N,N-dimethyl-formamide T=100°C; 2 h;
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
potassium hydroxide anschliessend Erwaermen mit Dimethylsulfat;
参考文献
Wittmer; Raiford
Journal of Organic Chemistry, 1945 , vol. 10, p. 527,528,530
Full Text View citing articles Show Details
Nair; Robinson
Journal of the Chemical Society, 1932 , p. 1236,1238
反应条件
1: 85 percent / ammonium acetate / acetic acid / 1.5 h
2: 35 percent / H2 / 10percent Pd/C / methanol / 2 h / 775.7 Torr
View Scheme
参考文献
Rogers, C. Bradford; Blum, Charles A.; Murphy, Bryan P.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 941 - 943
反应条件
1: 90 percent / K2CO3 / dimethylformamide / 2 h / 100 °C
2: 1.) FeSO4 x 7 H2O; 25 percent NH4OH; 2.) 10 percent H2SO4; NaNO2; KI / 2.) CuI / 1.) 5 min, 100 deg C 2.) AcOH, H2O
View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
1: 90 percent / K2CO3 / dimethylformamide / 2 h / 100 °C
2: FeSO4*7H2O, 25 percent NH4OH / 0.08 h / 100 °C
3: 20 percent HBr; NaNO2; 47 percent HBr / CuBr
View Scheme
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
