1-(2,6-二氯苯基)吲哚-2,3-二酮合成路线 （共 5 条）
反应条件
aluminium trichloride in various solvent(s) 20 h; Ambient temperature;
参考文献
Moser; Sallmann; Wiesenberg
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2358 - 2368
反应条件
1: benzene / 2 h / Ambient temperature 2: AlCl3 / various solvent(s) / 20 h / Ambient temperature View Scheme
参考文献
Moser; Sallmann; Wiesenberg
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2358 - 2368
反应条件
1: sodium 2-[(2,6-dichlorophenyl)-amino]phenyl-acetate With β-cyclodextrin complexation; 2: With water T=19.85°C; Cyclization; oxidation; 17532 h; 3: methanol Esterification;
参考文献
Hladon, Teresa; Cwiertnia
Pharmazie, 1999 , vol. 54, # 12 p. 943 - 944
反应条件
T=79.85°C; Decomposition; 17532 h; KineticsActivation energyThermodynamic data; Further Variations:Temperatures;
参考文献
Cwiertnia, Barbara; Hladon, Teresa; Stobiecki, Maciej
Journal of Pharmacy and Pharmacology, 1999 , vol. 51, # 11 p. 1213 - 1218
反应条件
1: 1 N NaOH / ethanol; H2O / 0.17 h / Heating 2: hydrazine hydrate, NaOCH3 / 2-methoxy-ethanol / 1.) from 60 deg C to 150 deg C, 2.) 150 deg C, 1 h View Scheme
参考文献
Moser; Sallmann; Wiesenberg
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2358 - 2368
