3-苄氧基-反-β-硝基苯乙烯合成路线 （共 13 条）
反应条件
1: 63 percent / LiAlH4 / tetrahydrofuran
2: 74 percent / triethylamine / diethyl ether / 1 h / Ambient temperature
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参考文献
Hocquaux; Marcot; Redeuilh; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 319 - 329
反应条件
1: 98 percent / LiAlH4 / CH2Cl2; diethyl ether / 0.5 h / Ambient temperature
2: 48 percent / aq. HCl / methanol / 3 h / Heating
3: 74 percent / ethanol / 1 h / 5 - 20 °C
4: 75 percent / 55 - 70 °C
5: 98 percent / MeONa / methanol / 12 h / 60 °C
6: 93 percent / K2CO3 / acetone / 12 h / 41 °C
7: 82 percent / LiAlH4 / CH2Cl2; diethyl ether / 0.5 h / Ambient temperature
8: 68 percent / diazabicyclooctane / dioxane / 7 h / 60 °C
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参考文献
Anderson, Wayne K.; McPherson, Howard L.; New, James S.; Rick, Arvela C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 10 p. 1321 - 1325
反应条件
1: 98 percent / LiAlH4 / CH2Cl2; diethyl ether / 0.5 h / Ambient temperature
2: 48 percent / aq. HCl / methanol / 3 h / Heating
3: 74 percent / ethanol / 1 h / 5 - 20 °C
4: 75 percent / 55 - 70 °C
5: 98 percent / MeONa / methanol / 12 h / 60 °C
6: 93 percent / K2CO3 / acetone / 12 h / 41 °C
7: 82 percent / LiAlH4 / CH2Cl2; diethyl ether / 0.5 h / Ambient temperature
8: 71 percent / diazabicyclooctane / dioxane / 48 h / 60 °C
View Scheme
参考文献
Anderson, Wayne K.; McPherson, Howard L.; New, James S.; Rick, Arvela C.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 10 p. 1321 - 1325
