4-氧代-4-(环己基氨基)-2-丁烯酸合成路线 （共 4 条）
反应条件
in acetic acid T=20°C; 8 h; Inert atmosphere;
参考文献
Salewska, Natalia; Boros-Majewska, Joanna; Lcka, Izabela; Chylinska, Katarzyna; Sabisz, Michal; Milewski, Slawomir; Milewska, Maria J.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 1 p. 117 - 124
参考文献
Onimura, Kenjiro; Matsushima, Mieko; Nakamura, Munetoshi; Tominaga, Tatsuya; Yamabuki, Kazuhiro; Oishi, Tsutomu
Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 16 p. 3550 - 3558
反应条件
tetrabutylammomium bromide; sodium carbonate; dimethyl sulfate in water; 1,2-dichloro-ethane T=20°C; 7 h;
参考文献
Deshpande, Sunita R.; Maybhate, Shailaja P.; Likhite, Anjali P.; Chaudhary, Preeti M.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010 , vol. 49, # 4 p. 487 - 488
反应条件
1: 1,1,1,3,3,3-hexamethyl-disilazane; benzene
2: bromine; acetic acid
3: bromine; sodium acetate; acetic acid
4: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; water; toluene / 90 °C / Inert atmosphere
View Scheme
参考文献
Onimura, Kenjiro; Matsushima, Mieko; Nakamura, Munetoshi; Tominaga, Tatsuya; Yamabuki, Kazuhiro; Oishi, Tsutomu
Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 16 p. 3550 - 3558
