N-(6-溴己基)邻苯二甲酰亚胺合成路线 （共 43 条）
反应条件
1: dimethylformamide / 80 °C 2: CBr4; PPh3 / acetonitrile / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 16 p. 4347 - 4351
反应条件
1: 80 percent / 0.25 h / 150 - 160 °C 2: 74.4 percent / CBr4/PPh3 / acetonitrile / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 46, # 6 p. 2047 - 2058
反应条件
T=170 - 180°C; 11 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 511 - 518
反应条件
1: hydrogen bromide / folgendes Erhitzen View Scheme
参考文献
Monatshefte fuer Chemie, , vol. 61, p. 221
反应条件
1: 1) hexamethyldisilazane, (NH4)2SO4 / 1) reflux, 20 h; 2) DMF, 80 deg C, 18 h 2: conc. HCl / acetic acid; H2O / 36 h / Heating 3: 1) 1,4-diazabicyclo<2.2.2>octane / 1) room temp., 15 min., DMSO; 2) 70 deg C, 18 h View Scheme
参考文献
Constant; Carden; Lhomme
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1035 - 1040
反应条件
1: sodium azide / N,N-dimethyl-formamide / 60 °C 2: hydrazine / water; ethanol / 60 °C View Scheme
参考文献
Loska, Rafal; Janiga, Anita; Gryko, Dorota
Journal of Porphyrins and Phthalocyanines, 2013 , vol. 17, # 1-2 p. 104 - 117
参考文献
Mediolanum Farmaceutici S.p.A.
Patent: US5302593 A1, 1994 ;
US 5302593 A
反应条件
1: 1.) NaH / 1.) DMF, 2 h, 2.) DMF, 100 deg C, 8 h 2: 1.) hydrazine hydrate, 2.) 4 N aq. HCl / 1.) EtOH, reflux, 8 h, 2.) EtOH, reflux, 6 h View Scheme
参考文献
Wright Jr.; Press; Chan; Marsico; Haug; Lucas; Tauber; Tomcufcik
Journal of Medicinal Chemistry, 1986 , vol. 29, # 4 p. 523 - 530
反应条件
in toluene 15 h; Heating;
参考文献
Agathocleous, Demetrios C.; Bulman Page, Philip C.; Cosstick, Richard; Galpin, Ian J.; McLennan, Alexander G.; Prescott, Mark
Tetrahedron, 1990 , vol. 46, # 6 p. 2047 - 2058
反应条件
1: (i) KOtBu, DMF, (ii) aq. HBr, AcOH 2: (i), (ii) NaBH4 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 21, p. 1126 - 1132
