3,5-二氯吡啶合成路线

1254473-64-74-[(1E)-2-[5-[(1R)-1-(3,5-二氯-4-吡啶基)乙氧基]-1H-吲唑-3-基]乙烯基]-1H-吡唑-1-乙醇

参考文献

ELI LILLY AND COMPANY
Patent: US2012/83511 A1, 2012 ;

参考文献

Armani, Elisabetta; Amari, Gabriele; Rizzi, Andrea; Fanti, Renato De; Ghidini, Eleonora; Capaldi, Carmelida; Carzaniga, Laura; Caruso, Paola; Guala, Matilde; Peretto, Ilaria; La Porta, Elena; Bolzoni, Pier T.; Facchinetti, Fabrizio; Carnini, Chiara; Moretto, Nadia; Patacchini, Riccardo; Bassani, Franco; Cenacchi, Valentina; Volta, Roberta; Amadei, Francesco; Capacchi, Silvia; Delcanale, Maurizio; Puccini, Paola; Catinella, Silvia; Civelli, Maurizio; Villetti, Gino
Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 793 - 816

2457-47-83,5-二氯吡啶+

144-55-8碳酸氢钠+

74-88-4甲基碘

100868-46-03,5-二氯-4-甲基吡啶

参考文献

Rhone-Poulenc Rorer Limited
Patent: US5679696 A1, 1997 ;

100868-46-03,5-二氯-4-甲基吡啶

参考文献

RHONE-POULENC RORER LIMITED
Patent: EP741707 B1, 1998 ;

2457-47-83,5-二氯吡啶

1370347-50-4(S)-1-(3,5-二氯吡啶-4-基)乙醇

参考文献

ELI LILLY AND COMPANY
Patent: US2012/83511 A1, 2012 ;

参考文献

Tamao, K.; Kodama, S.; Nakajima, I.; Kumada, M.; Minato, A.; Suzuki, K.
Tetrahedron, 1982 , vol. 38, # 22 p. 3347 - 3354

2457-47-83,5-二氯吡啶

15177-57-83,5-二氯吡啶 1-氧化物

参考文献

Chambers, Richard D.; Hall, Christopher W.; Hutchinson, John; Millar, Ross W.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 10 p. 1705 - 1713

2457-47-83,5-二氯吡啶

109705-15-9

参考文献

Umemoto, Teruo; Harasawa, Kikuko; Tomizawa, Ginjiro; Kawada, Kosuke; Tomita, Kyoichi
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 4 p. 1081 - 1092

2457-47-83,5-二氯吡啶

70999-08-53,5-双(甲基硫代)吡啶

参考文献

Testaferri, Lorenzo; Tiecco, Marcello; Tingoli, Marco; Bartoli, Donatella; Massoli, Alberto
Tetrahedron, 1985 , vol. 41, # 7 p. 1373 - 1384

2457-47-83,5-二氯吡啶+

5188-07-8

70999-08-53,5-双(甲基硫代)吡啶

参考文献

Tiecco, Marcello
Bulletin des Societes Chimiques Belges, 1986 , vol. 95, # 11 p. 1009 - 1020