乙酰基-赖氨酰(乙酰基)-D-丙氨酰-D-丙氨酸合成路线 (共 5 条)
反应条件
1: 1,2-dimethoxy-ethane
2: 1.) hydrogen / 2.) water
View Scheme
参考文献
Williams; Williamson; Butcher; Hammond
Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1332 - 1339
反应条件
1: 1,2-dimethoxy-ethane
2: 1.) hydrogen / 2.) water
View Scheme
参考文献
Williams; Williamson; Butcher; Hammond
Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1332 - 1339
反应条件
hydrogen
2.) water; Multistep reaction;
参考文献
Williams; Williamson; Butcher; Hammond
Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1332 - 1339
反应条件
1: Fmoc-DL-Ala-OH With N-(4,6-dimethoxy-1,3,5-triazin-2-yl)strychninium tetrafluoroborate; [3H]-Strychnine in acetonitrile
T=0°C; 0.25 h;
2: With 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine in dichloromethane; acetonitrile
10 h; Wang resin;
3: Fmoc-DL-Ala-OH; acetic anhydride; ε-FmocHN-Lys(α-Fmoc)OH Further stages;
参考文献
Kolesinska, Beata; Kasperowicz-Frankowska, Katarzyna; Fraczyk, Justyna; Kaminski, Zbigniew J.
Helvetica Chimica Acta, 2012 , vol. 95, # 11 p. 2084 - 2098
参考文献
Yan, Husheng; Qi, Dongfeng; Cheng, Xiaohui; Song, Zhengji; Li, Wenlan; He, Binglin
Journal of Antibiotics, 1998 , vol. 51, # 8 p. 750 - 756