L-亮氨酸苄酯盐酸盐(1:1)合成路线 （共 10 条）
反应条件
thionyl chloride T=5°C; 5.33333 h; Heating;
参考文献
You, Jun; Liu, Bo; Wang, Yi
Journal of the Chinese Chemical Society, 2009 , vol. 56, # 5 p. 1010 - 1017
反应条件
hydrogenchloride in ethyl acetate
参考文献
Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 27, # 2 p. 302 - 310
反应条件
1: tetra-(n-butyl)ammonium iodide; potassium carbonate; potassium iodide / acetone 2: hydrogenchloride / ethyl acetate View Scheme
参考文献
Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 27, # 2 p. 302 - 310
参考文献
Biondini, Daniele; Brinchi, Lucia; Germani, Raimondo; Goracci, Laura; Savelli, Gianfranco
Letters in Organic Chemistry, 2010 , vol. 7, # 1 p. 39 - 44
反应条件
1: sodium hydroxide / methanol 2: tetra-(n-butyl)ammonium iodide; potassium carbonate; potassium iodide / acetone 3: hydrogenchloride / ethyl acetate View Scheme
参考文献
Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 27, # 2 p. 302 - 310
反应条件
1.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere 1.2: 12 h / Inert atmosphere 2.1: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 12 h / 0 °C / Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 18, # 21 p. 6528 - 6541
反应条件
T=90°C; 5 h; Ionic liquidInert atmosphere;
参考文献
Letters in Organic Chemistry, , vol. 7, # 1 p. 39 - 44
反应条件
1: chlorocarbonic acid butyl ester 2: palladium; aqueous ethanol acetic acid View Scheme
参考文献
Bryant et al.
Journal of the Chemical Society, 1959 , p. 3868,3870
反应条件
1: 98 percent / Et3N / 0 - 20 °C 2: 86 percent / Cl3CO2CCl; NMM / CH2Cl2 / -40 - -15 °C 3: 65 percent / TFA; Py / CH2Cl2 / 0 - 20 °C 4: 29 percent / H2 / Pd/C View Scheme
参考文献
Semple, J. Edward; Owens, Timothy D.; Nguyen, Khanh; Levy, Odile E.
Organic Letters, 2000 , vol. 2, # 18 p. 2769 - 2772
反应条件
1: triethylamine 2: palladium / Hydrogenation View Scheme
参考文献
Stelakatos et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 2884,2887
