N-苄基-N-环丙基环丙胺合成路线 （共 4 条）
反应条件
titanium(IV) isopropylate in tetrahydrofuran; diethyl ether T=20°C; Grignard reaction; Cyclization; 24 h;
参考文献
De Meijere, Armin; Chaplinski, Vladimir; Gerson, Fabian; Merstetter, Pascal; Haselbach, Edwin
Journal of Organic Chemistry, 1999 , vol. 64, # 19 p. 6951 - 6959
反应条件
MeTi(OiPr)3 in tetrahydrofuran; diethyl ether T=20°C; 16 h; Inert atmosphere;
参考文献
De Meijere, Armin; Chaplinski, Vladimir; Winsel, Harald; Kordes, Markus; Stecker, Bjoern; Gazizova, Vesta; Savchenko, Andrei I.; Boese, Roland; Schill, Farina
Chemistry - A European Journal, 2010 , vol. 16, # 46 p. 13862 - 13875
反应条件
1: 96 percent / NaH / benzene / 10 h / 40 °C 2: 83 percent / Ti(OiPr)4 / tetrahydrofuran; diethyl ether / 24 h / 20 °C View Scheme
参考文献
De Meijere, Armin; Chaplinski, Vladimir; Winsel, Harald; Kordes, Markus; Stecker, Bjoern; Gazizova, Vesta; Savchenko, Andrei I.; Boese, Roland; Schill, Farina
Chemistry - A European Journal, 2010 , vol. 16, # 46 p. 13862 - 13875
反应条件
hydrogen; palladium on activated charcoal
Hydrogenolysis;
参考文献
De Meijere, Armin; Chaplinski, Vladimir; Winsel, Harald; Kusnetsov, Mikhael A.; Rademacher, Paul; Boese, Roland; Haumann, Thomas; Traetteberg, Marit; Schleyer, Paul Von R.; Zywietz, Tosja; Jiao, Haijun; Merstetter, Pascal; Gerson, Fabian
Angewandte Chemie - International Edition, 1999 , vol. 38, # 16 p. 2430 - 2433
