3-N-苄氧羰基氨基-2,6-二氧代哌啶合成路线 （共 8 条）
反应条件
1: H2, aq. HCl / 10 percent Pd/C / ethyl acetate / 2585.74 - 3102.89 Torr 2: AcOH / Heating 3: H2 / 10 percent Pd/C / acetone / 2585.74 - 3102.89 Torr View Scheme
参考文献
Muller, George W.; Chen, Roger; Huang, Shaei-Yun; Corral, Laura G.; Wong, Lu Min; Patterson, Rebecca T.; Chen, Yuxi; Kaplan, Gilla; Stirling, David I.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1625 - 1630
反应条件
1: H2, aq. HCl / 10 percent Pd/C / ethyl acetate / 2585.74 - 3102.89 Torr 2: AcOH / Heating View Scheme
参考文献
Muller, George W.; Chen, Roger; Huang, Shaei-Yun; Corral, Laura G.; Wong, Lu Min; Patterson, Rebecca T.; Chen, Yuxi; Kaplan, Gilla; Stirling, David I.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1625 - 1630
反应条件
hydrogen; palladium 10 on activated carbon in tetrahydrofuran; methanol T=20°C; 2 h;
参考文献
Tianjin Hemey Bio-Tech Co., Ltd.
Patent: EP2093228 A1, 2009 ;
Location in patent: Page/Page column 13 ;
反应条件
1: 3-(benzyloxycarbonyl)-amino-2,6-dioxopiperidine With palladium 10 on activated carbon; hydrogen in methanol T=25 - 35°C; 2 h; 2: 2-(bromomethyl)-3-nitrobenzoic acid,methyl ester With triethylamine in N,N-dimethyl-formamide T=25 - 35°C; 6 h;
参考文献
HETERO RESEARCH FOUNDATION; PARTHASARADHI REDDY, Bandi; RATHNAKAR REDDY, Kura; MURALIDHARA REDDY, Dasari; RAMAKRISHNA REDDY, Matta; VAMSI KRISHNA, Bandi
Patent: WO2013/5229 A1, 2013 ;
Location in patent: Page/Page column 8 ;
反应条件
1: H2, aq. HCl / 10 percent Pd/C / ethyl acetate / 2585.74 - 3102.89 Torr 2: Et3N / dimethylformamide / 80 °C View Scheme
参考文献
Muller, George W.; Chen, Roger; Huang, Shaei-Yun; Corral, Laura G.; Wong, Lu Min; Patterson, Rebecca T.; Chen, Yuxi; Kaplan, Gilla; Stirling, David I.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1625 - 1630
反应条件
1: H2, aq. HCl / 10 percent Pd/C / ethyl acetate / 2585.74 - 3102.89 Torr 2: Et3N / dimethylformamide / 80 °C 3: H2 / 10 percent Pd/C / methanol View Scheme
参考文献
Muller, George W.; Chen, Roger; Huang, Shaei-Yun; Corral, Laura G.; Wong, Lu Min; Patterson, Rebecca T.; Chen, Yuxi; Kaplan, Gilla; Stirling, David I.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1625 - 1630
反应条件
1: H2, aq. HCl / 10 percent Pd/C / ethyl acetate / 2585.74 - 3102.89 Torr 2: AcOH / Heating 3: H2 / 10 percent Pd/C / acetone / 2585.74 - 3102.89 Torr View Scheme
参考文献
Muller, George W.; Chen, Roger; Huang, Shaei-Yun; Corral, Laura G.; Wong, Lu Min; Patterson, Rebecca T.; Chen, Yuxi; Kaplan, Gilla; Stirling, David I.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1625 - 1630
反应条件
1: H2, aq. HCl / 10 percent Pd/C / ethyl acetate / 2585.74 - 3102.89 Torr
2: AcOH / Heating
View Scheme
参考文献
Muller, George W.; Chen, Roger; Huang, Shaei-Yun; Corral, Laura G.; Wong, Lu Min; Patterson, Rebecca T.; Chen, Yuxi; Kaplan, Gilla; Stirling, David I.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 11 p. 1625 - 1630
