3-甲基苯并呋喃-2-羧酸合成路线 （共 24 条）
反应条件
potassium hydroxide in methanol 24 h; Ambient temperature;
参考文献
Bedford, Simon B.; Begley, Michael J.; Cornwall, Philip; Foreman, Joel P.; Knight, David W.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 23 p. 2827 - 2832
反应条件
sodium acetate; acetic anhydride T=110°C; 3 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 56, # 9 p. 2762 - 2767
反应条件
tert.-butyl lithium in tetrahydrofuran; pentane 1.) -100 deg C, 5 h, 2.) 1 h;
参考文献
Topolski, Marek
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5588 - 5594
反应条件
potassium hydroxide in 1,4-dioxane T=60°C; 6 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 29, # 2 p. 423 - 429
反应条件
potassium carbonate; butanone Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge;
参考文献
Journal of the American Chemical Society, , vol. 73, p. 872
Nippon Kagaku Zasshi, , vol. 72, p. 307
Journal of the American Chemical Society, , vol. 73, p. 872
反应条件
1: 50 percent / n-butyllithium / tetrahydrofuran; hexane / 1.) -90 deg C, 15 min, 2.) r.t., overnight 2: 85 percent / conc. aq.HCl / tetrahydrofuran / 3 h / Ambient temperature 3: 70 percent / t-BuLi / tetrahydrofuran; pentane / 1.) -100 deg C, 5 h, 2.) 1 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 17 p. 5588 - 5594
反应条件
1: 75 percent / KOtBu / tetrahydrofuran / 1.) 15 min, 2.) 2 h 2: 50 percent / n-butyllithium / tetrahydrofuran; hexane / 1.) -90 deg C, 15 min, 2.) r.t., overnight 3: 85 percent / conc. aq.HCl / tetrahydrofuran / 3 h / Ambient temperature 4: 70 percent / t-BuLi / tetrahydrofuran; pentane / 1.) -100 deg C, 5 h, 2.) 1 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 17 p. 5588 - 5594
反应条件
1: 85 percent / conc. aq.HCl / tetrahydrofuran / 3 h / Ambient temperature 2: 70 percent / t-BuLi / tetrahydrofuran; pentane / 1.) -100 deg C, 5 h, 2.) 1 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 17 p. 5588 - 5594
反应条件
1: 65 percent / 12 M H2SO4 / 1 h / -10 °C 2: 97 percent / KOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 23 p. 2827 - 2832
参考文献
Helvetica Chimica Acta, , vol. 31, p. 78,80
