2-(4-羟基丁基)-1H-异吲哚-1,3(2H)-二酮合成路线 （共 13 条）
反应条件
1: CrO3, pyridine / CH2Cl2 / 0.5 h / 25 °C
2: 89 percent / BF3-etherate / diethyl ether / 25 °C
3: 82 percent / acetone / 0.42 h / 10 - 20 °C / Irradiation
4: 58 percent / Raney Ni / ethanol / 2 h / Heating
View Scheme
参考文献
Wada, Masao; Nakai, Hideo; Sato, Yasuhiko; Hatanaka, Yasumaru; Kanaoka, Yuichi
Tetrahedron, 1983 , vol. 39, # 16 p. 2691 - 2698
反应条件
1: CrO3, pyridine / CH2Cl2 / 0.5 h / 25 °C
2: 69 percent / BF3-etherate / diethyl ether / 25 °C
View Scheme
参考文献
Wada, Masao; Nakai, Hideo; Sato, Yasuhiko; Hatanaka, Yasumaru; Kanaoka, Yuichi
Tetrahedron, 1983 , vol. 39, # 16 p. 2691 - 2698
反应条件
1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane
2: sodium tris(acetoxy)borohydride / dichloromethane
View Scheme
参考文献
Crawford, Jason B.; Chen, Gang; Gauthier, David; Wilson, Trevor; Carpenter, Bryon; Baird, Ian R.; McEachern, Ernie; Kaller, Alan; Harwig, Curtis; Atsma, Bem; Skerlj, Renato T.; Bridger, Gary J.
Organic Process Research and Development, 2008 , vol. 12, # 5 p. 823 - 830
