1: 78 percent / dimethylsulfoxide / 72 h / 50 °C 2: 74 percent / NaHCO3; NaI / dimethylformamide / 7 h / 20 °C 3: SOCl2 / CH2Cl2 / 2 h / Heating 4: 380 mg / LiHMDS / tetrahydrofuran / 2 h / -78 - 20 °C View Scheme

1: 74 percent / NaHCO3; NaI / dimethylformamide / 7 h / 20 °C 2: SOCl2 / CH2Cl2 / 2 h / Heating 3: 380 mg / LiHMDS / tetrahydrofuran / 2 h / -78 - 20 °C View Scheme

hydrogen; palladium on activated charcoal in methanol 96 h;