1.1: pyridine; thionyl chloride / tetrahydrofuran / -45 °C / Inert atmosphere 2.1: tetrahydrofuran; diethyl ether / -78 - 0 °C / Inert atmosphere 3.1: lithium hexamethyldisilazane / tetrahydrofuran; diethyl ether / 0 - 20 °C / Inert atmosphere 3.2: 20 °C / Inert atmosphere View Scheme

1.1: tetrahydrofuran / Inert atmosphere 2.1: pyridine; thionyl chloride / tetrahydrofuran / -45 °C / Inert atmosphere 3.1: tetrahydrofuran; diethyl ether / -78 - 0 °C / Inert atmosphere 4.1: lithium hexamethyldisilazane / tetrahydrofuran; diethyl ether / 0 - 20 °C / Inert atmosphere 4.2: 20 °C / Inert atmosphere View Scheme

1.1: sodium hydrogencarbonate / ethyl acetate / Inert atmosphere 2.1: tetrahydrofuran / Inert atmosphere 3.1: pyridine; thionyl chloride / tetrahydrofuran / -45 °C / Inert atmosphere 4.1: tetrahydrofuran; diethyl ether / -78 - 0 °C / Inert atmosphere 5.1: lithium hexamethyldisilazane / tetrahydrofuran; diethyl ether / 0 - 20 °C / Inert atmosphere 5.2: 20 °C / Inert atmosphere View Scheme

1: tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere 2: lithium hexamethyldisilazane / tetrahydrofuran; N,N-dimethyl-formamide / 0.5 h / 20 °C / Inert atmosphere View Scheme

1.1: tetrahydrofuran; diethyl ether / -78 - 0 °C / Inert atmosphere 2.1: lithium hexamethyldisilazane / tetrahydrofuran; diethyl ether / 0 - 20 °C / Inert atmosphere 2.2: 20 °C / Inert atmosphere View Scheme

1: tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere 2: ammonia; lithium; iron nitrate (III) / tetrahydrofuran / 0.75 h / -78 °C / Inert atmosphere View Scheme

1: 92 percent / DEAD / tetrahydrofuran / 0.67 h / 0 - 25 °C 2: benzene / 1.5 h / 40 °C 3: tetrahydrofuran / 0.25 h / -70 °C 4: TFA / CH2Cl2 / 1 h / 0 - 25 °C View Scheme