反应条件
1.1: KHMDS / toluene; tetrahydrofuran / 2 h
2.1: tetrahydrofuran / 0.75 h
2.2: CAN / acetonitrile / 5 h / 0 - 20 °C
3.1: 57 percent / MCPBA; K2CO3 / CH2Cl2 / 0.5 h
4.1: O3 / CH2Cl2 / 0.03 h / -78 °C
4.2: 18 percent / NaBH4/Al2O3 / benzene / 14 h / 20 °C
5.1: 40 percent / SmI2 / tetrahydrofuran; 2-methyl-propan-2-ol / 0.08 h
6.1: 77 percent / TFA; anisole / CH2Cl2 / 0.42 h / -20 - -10 °C
View Scheme
参考文献
Bates, Roderick W.; Fernandez-Megia, Eduardo; Ley, Steven V.; Ruck-Braun, Karola; Matthew Tilbrook
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 14 p. 1917 - 1925
