反应条件
1: 4-bromo-3-benzyloxybenzoic acid With 1,1'-carbonyldiimidazole in N,N-dimethyl-formamide T=40°C; 3 h; 2: tert-butyl alcohol With 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=55°C; 40 h; Further stages.;
参考文献
Lampe, John W.; Jagdmann Jr., G. Erik; Johnson, Mary George; Lai, Yen-Shi; Lowden, Christopher T.; Lynch, Michael P.; Mendoza, Jose S.; Murphy, Marcia M.; Wilson, Joseph W.; Ballas, Lawrence M.; Carter, Kiyomi; Biggers, Christopher K.; Darges, James W.; Davis, Jefferson E.; Hubbard, Frederick R.; Stamper, Mark L.; Defauw, Jean M.; Foglesong, Robert J.; Hall, Steven E.; Heerding, Julia M.; Hollinshead, Sean P.; Hu, Hong; Hughes, Philip F.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 12 p. 2624 - 2643
