1: 2-N-iso-butyl-2-oxoethyl phosphonium chloride With potassium tert-butylate in tetrahydrofuran
T=20°C; Wittig reaction; 0.5 h;
2: (E)-2-decenal in tetrahydrofuran
T=0°C; Wittig reaction; 2 h;
参考文献
Matovic, Nicholas J.; Hayes, Patricia Y.; Penman, Kerry; Lehmann, Reginald P.; De Voss, James J.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4467 - 4481
potassium tert-butylate in tetrahydrofuran
T=0°C; Wittig reaction;
参考文献
Matovic, Nicholas J.; Hayes, Patricia Y.; Penman, Kerry; Lehmann, Reginald P.; De Voss, James J.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4467 - 4481
1: toluene / 2 h / 80 °C
2: potassium tert-butylate / tetrahydrofuran / 0 °C
View Scheme
参考文献
Matovic, Nicholas J.; Hayes, Patricia Y.; Penman, Kerry; Lehmann, Reginald P.; De Voss, James J.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4467 - 4481
1.1: diisobutylaluminium hydride / diethyl ether / 0 °C
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 - -10 °C
2.2: -78 - 20 °C
3.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 20 °C
3.2: 2 h / 0 °C
View Scheme
参考文献
Matovic, Nicholas J.; Hayes, Patricia Y.; Penman, Kerry; Lehmann, Reginald P.; De Voss, James J.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4467 - 4481
1.1: sodium hydride / diethyl ether; mineral oil / 0 °C
1.2: 0 °C
2.1: diisobutylaluminium hydride / diethyl ether / 0 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 - -10 °C
3.2: -78 - 20 °C
4.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 20 °C
4.2: 2 h / 0 °C
View Scheme
参考文献
Matovic, Nicholas J.; Hayes, Patricia Y.; Penman, Kerry; Lehmann, Reginald P.; De Voss, James J.
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4467 - 4481
