4,6-二氟吲哚-2-羧酸合成路线 (共 4 条)
反应条件
1: With sodium hydroxide; water in ethanol 0.25 h; Heating / reflux; 2: With hydrogenchloride in water
参考文献
US2008/27122 A1, ;
Page/Page column 11 ;
反应条件
sodium hydroxide 2.5 h; Heating;
参考文献
Bozilovic, Jelena; Bats, Jan W.; Engels, Joachim W.
Canadian Journal of Chemistry, 2007 , vol. 85, # 4 p. 283 - 292
反应条件
1.1: MeONa / 14 h / -20 - 4 °C 1.2: 73 percent / xylene / Heating 2.1: 99 percent / aq. NaOH / 2.5 h / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 85, # 4 p. 283 - 292
反应条件
1-methyl-pyrrolidin-2-one; copper T=240°C;
参考文献
Bozilovic, Jelena; Engels, Joachim W.
Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 8-9 p. 869 - 871