2-(4-甲氧基苯基)-1-苯基乙酮合成路线 （共 113 条）
反应条件
sodium t-butanolate; palladium diacetate; 2'-hydroxy-2-di-cyclohexylphosphinobiphenyl-4'-sulfonic acid in N,N-dimethyl-formamide T=80°C; 14.75 h;
参考文献
Meudt, Andreas; Nerdinger, Sven; Lehnemann, Bernd Wilhelm; Vogel, Till; Snieckus, Victor
Patent: US2008/221350 A1, 2008 ;
Location in patent: Page/Page column 5 ;
反应条件
C41H46Cl2FeN4Pd; potassium tert-butylate in 1,4-dioxane T=100°C; 3 h; Inert atmosphere;
参考文献
Xu, Chen; Li, Hong-Mei; Wang, Zhi-Qiang; Fu, Wei-Jun; Zhang, Yu-Qing; Ji, Bao-Ming
Australian Journal of Chemistry, 2012 , vol. 65, # 4 p. 366 - 370
反应条件
aluminium trichloride in dichloromethane Ambient temperature;
参考文献
Lantos, I.; Bender, P. E.; Razgaitis, K. A.; Sutton, B. M.; DiMartino, M. J.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 72 - 75
反应条件
sodium t-butanolate; (SIPr)Pd(allyl)Cl in tetrahydrofuran T=60°C; 1 h;
参考文献
Viciu, Mihai S.; Germaneau, Romain F.; Nolan, Steven P.
Organic Letters, 2002 , vol. 4, # 23 p. 4053 - 4055
反应条件
potassium phosphate; Pd(OAc)2*n-butylbis(1-adamantyl)phosphine in 1,4-dioxane T=100°C; 20 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 344, # 2 p. 209 - 217
反应条件
1: With 2-Iodo-5-methylbenzenesulfonic acid in tert-butyl methyl ether; water; isopropyl alcohol T=22°C; 0.0833333 h; Inert atmosphere; 2: With Oxonereg; in tert-butyl methyl ether; water; isopropyl alcohol T=22°C; 46 h; Inert atmosphere; regioselective reaction; Further stages;
参考文献
Purohit, Vikram C.; Allwein, Shawn P.; Bakale, Roger P.
Organic Letters, 2013 , vol. 15, # 7 p. 1650 - 1653
反应条件
in tetrahydrofuran T=-78 - 20°C; 1 h;
参考文献
CHROMA THERAPEUTICS LTD
Patent: WO2006/117552 A1, 2006 ;
Location in patent: Page/Page column 177-179 ;
WO 2006/117552 A1
反应条件
piperidine; Ru(bpy)3Cl2 in acetonitrile T=25°C; 6 h; Irradiation; Reagent/catalystSolventTime;
参考文献
Sun, Hongnan; Yang, Chao; Gao, Fei; Li, Zhe; Xia, Wujiong
Organic Letters, 2013 , vol. 15, # 3 p. 624 - 627
反应条件
diethylzinc in dichloromethane T=20°C; 2 h;
参考文献
Li, Lezhen; Cai, Peijie; Guo, Qingxiang; Xue, Song
Journal of Organic Chemistry, 2008 , vol. 73, # 9 p. 3516 - 3522
反应条件
[NiCl2(1,2-dimethoxyethane)]; 1,3-bis-(diphenylphosphino)propane; water; zinc in ethylene glycol dimethyl ether T=100°C; 36 h;
参考文献
Hsieh, Jen-Chieh; Chen, Yen-Chung; Cheng, An-Yi; Tseng, Hsiao-Chun
Organic Letters, 2012 , vol. 14, # 5 p. 1282 - 1285
