2-溴-2′-羟基苯乙酮合成路线 （共 26 条）
反应条件
in N,N-dimethyl-formamide
T=40 - 45°C; 5 h;
参考文献
Emami, Saeed; Foroumadi, Alireza
Archiv der Pharmazie, 2009 , vol. 342, # 9 p. 541 - 545
反应条件
sodium acetate
T=180°C;
参考文献
Vargha et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 2652,2654
参考文献
Vargha et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 2652,2654
反应条件
1: 80 percent / NH2OH*HCl / methanol / Ambient temperature
2: 72 percent / ethanol; H2O / 1 h / 60 °C
View Scheme
参考文献
Mohareb, Rafat Milad; Sherif, Sherif Mourad; Shams, Hoda Zaki; El-Torgoman, Abdel Moneim
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1990 , vol. 45, # 7 p. 1067 - 1071
反应条件
1: 83 percent / dioxane; ethanol / 1 h / Ambient temperature
2: 95 percent / m-chloroperoxybenzoic acid (m-CPBA) / CH2Cl2 / 5 h / 0 °C
3: 56 percent / sodium formate / 1) 70-75 deg C, 3 h, 2) room temp., 1 h
4: 1) THF, -78 - 0 deg C, 2) CDCl3, 140 deg C, 1 h
View Scheme
参考文献
Saengchantara, Suthiweth T.; Wallace, Timothy W.
Tetrahedron, 1990 , vol. 46, # 18 p. 6553 - 6564
反应条件
1: 75 percent / potassium hydroxide / ethanol / 2 h / Heating
2: K2CO3 / acetone
View Scheme
参考文献
Joshi, U. K.; Paradkar, M. V.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 378 - 379
