2,5-二(4-甲基苯基)-1,3,4-恶二唑合成路线 （共 20 条）
反应条件
in diethyl ether 28 h; Irradiation;
参考文献
Chemische Berichte, , vol. 113, # 7 p. 2566 - 2574
反应条件
1: aniline With AlCl3, aluminium chloride T=130 - 140°C; 2: 2,5-bis(4-methylphenyl)-1,3,4-oxadiazole in 1-methyl-pyrrolidin-2-one T=205 - 215°C; 7 h;
参考文献
Chiriac, Constantin I.; Tanasa, Fulga; Nechifor, Marioara
Revue Roumaine de Chimie, 2010 , vol. 55, # 3 p. 175 - 177
反应条件
1: With copper diacetate; palladium diacetate; trifluoroacetic acid in ethylene glycol dimethyl ether
T=120°C; 24 h; Inert atmosphereSealed tube;
2: With potassium carbonate in ethylene glycol dimethyl ether; water
T=20°C;
参考文献
Wang, Min; Li, Dengke; Zhou, Wei; Wang, Lei
Tetrahedron, 2012 , vol. 68, # 7 p. 1926 - 1930
反应条件
DMEG; triethylamine in dichloromethane
T=20°C; Dehydration; Cyclization; 21 h;
参考文献
Isobe, Toshio; Ishikawa, Tsutomu
Journal of Organic Chemistry, 1999 , vol. 64, # 19 p. 6989 - 6992
反应条件
hydraziniumdihydrochloride; phosphoric acid; trichlorophosphate in water
T=140°C; Condensation; 2 h;
参考文献
Bentiss, Fouad; Lagrenee, Michel
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 4 p. 1029 - 1032
反应条件
trichloroisocyanuric acid in ethanol
T=20°C; 0.5 h;
参考文献
Pore; Mahadik; Desai
Synthetic Communications, 2008 , vol. 38, # 18 p. 3121 - 3128
反应条件
1,4-diaza-bicyclo[2.2.2]octane; tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; potassium carbonate in methanol; hexane
T=60°C; 4 h;
参考文献
Gao, Peng; Wei, Yunyang
Journal of Chemical Research, 2013 , vol. 37, # 8 p. 506 - 510
反应条件
pyridine
12 h; Heating / reflux;
参考文献
Qiu, Chunong; Xiao, Steven; Qiu, Cindy Xing
Patent: US2006/36097 A1, 2006 ;
Location in patent: Page/Page column 5 ;
反应条件
1: With hydrazine hydrate in tetrahydrofuran
Heating;
2: With PPA in tetrahydrofuran
T=130°C; 2.5 h;
参考文献
Park, Yong-Dae; Kim, Jeum-Jong; Chung, Hyun-A; Kweon, Deok-Heon; Cho, Su-Dong; Lee, Sang-Gyeong; Yoon, Yong-Jin
Synthesis, 2003 , # 4 p. 560 - 564
反应条件
bis-[(trifluoroacetoxy)iodo]benzene in dimethyl sulfoxide
T=20°C; 0.166667 h;
参考文献
Shang, Zhenhua; Reiner, John; Chang, Junbiao; Zhao, Kang
Tetrahedron Letters, 2005 , vol. 46, # 15 p. 2701 - 2704
