(R)-(-)-3-羟基丁酸乙酯合成路线 (共 32 条)
反应条件
Fala baker' yeast; allyl alcohol
参考文献
Tetrahedron Letters, , vol. 42, # 7 p. 1267 - 1268
反应条件
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 10 p. 2199 - 2210
反应条件
scandium tris(trifluoromethanesulfonate) T=64°C; 10 h;
参考文献
Remme, Nicole; Koschek, Katharina; Schneider, Christoph
Synlett, 2007 , # 3 p. 491 - 493
反应条件
ee = 96percent; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Genet, J. P.; Juge, S.; Mallart, S.
Tetrahedron Letters, 1988 , vol. 29, # 51 p. 6765 - 6768
参考文献
Ishigami, Ken; Kitahara, Takeshi
Tetrahedron, 1995 , vol. 51, # 23 p. 6431 - 6442
反应条件
sodium hydroxide; silver nitrate in diethyl ether 3 h; Heating; Title compound not separated from byproducts;
参考文献
Chemische Berichte, , vol. 121, p. 2035 - 2044
反应条件
1: triethylamine / dichloromethane 2: calcium carbonate; water View Scheme
参考文献
Zheng, Jian-Feng; Lan, Hong-Qiao; Yang, Rui-Feng; Peng, Qi-Long; Xiao, Zhen-Hua; Tuo, Shi-Chuan; Hu, Kong-Zhen; Xiang, Yong-Gang; Wei, Zhen; Huang, Pei-Qiang; Zhang, Zhen
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1799 - 1808,10
反应条件
potassium hydroxide T=0°C; 24 h;
参考文献
Seebach, Dieter; Zueger, Max
Helvetica Chimica Acta, 1982 , vol. 65, # 2 p. 495 - 503
反应条件
N,N-bis-2-(hydroxyethyl)-2-amino ethane sulfonic acid; lipase from Ophiostoma piliferum in water T=25°C; pH=7.20; Enzyme kinetics;
参考文献
Liu, Andrew Man Fai; Somers, Neil A.; Kazlauskas, Romas J.; Brush, Terry S.; Zocher, Frank; Enzelberger, Markus M.; Bornscheuer, Uwe T.; Horsman, Geoff P.; Mezzetti, Alessandra; Schmidt-Dannert, Claudia; Schmid, Rolf D.
Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 545 - 556
反应条件
lithium aluminium tetrahydride in diethyl ether 1 h; Ambient temperature;
参考文献
Mori, Kenji; Miyake, Masahiro
Tetrahedron, 1987 , vol. 43, # 10 p. 2229 - 2240