1: 46 percent / partial hydrolysis 2: 96.9 percent / 1.) phosphoryl chloride; 2.) conc.HCl / 1.) 30 deg C, 10 min; 2.) 30 to 40 deg C, 10 min; 40 deg C, 10 min 3: 18.7 percent / K2CO3 / methanol; H2O / 0.5 h / Heating View Scheme

1.1: [bis(acetoxy)iodo]benzene; tetra-(n-butyl)ammonium iodide / acetonitrile / Inert atmosphere 2.1: water; lithium hydroxide hydrate / tetrahydrofuran / 18 °C / Inert atmosphere 2.2: Amberlyst 15 ion exchange resin / 1 h / Inert atmosphere 3.1: pyridine; thionyl chloride / 4 h / 20 °C / Inert atmosphere View Scheme