5-羟基-6-甲氧基-1H-吲哚-2-羧酸合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=25°C; P=760 Torr; 2 h;
参考文献
Tichenor, Mark S.; Kastrinsky, David B.; Boger, Dale L.
Journal of the American Chemical Society, 2004 , vol. 126, # 27 p. 8396 - 8398
反应条件
1: 87 percent / NaOMe / tetrahydrofuran; methanol / 25 h / -18 - 4 °C 2: 72 percent / xylene / 14 h / 140 °C 3: 93 percent / aq. LiOH / methanol; tetrahydrofuran / 4 h / 25 °C 4: 38 percent / H2 / Pd/C / tetrahydrofuran; methanol / 3 h / 25 °C / 760 Torr View Scheme
参考文献
Tichenor, Mark S.; Kastrinsky, David B.; Boger, Dale L.
Journal of the American Chemical Society, 2004 , vol. 126, # 27 p. 8396 - 8398
反应条件
1: 93 percent / aq. LiOH / methanol; tetrahydrofuran / 4 h / 25 °C 2: 38 percent / H2 / Pd/C / tetrahydrofuran; methanol / 3 h / 25 °C / 760 Torr View Scheme
参考文献
Tichenor, Mark S.; Kastrinsky, David B.; Boger, Dale L.
Journal of the American Chemical Society, 2004 , vol. 126, # 27 p. 8396 - 8398
反应条件
1: 72 percent / xylene / 14 h / 140 °C 2: 93 percent / aq. LiOH / methanol; tetrahydrofuran / 4 h / 25 °C 3: 38 percent / H2 / Pd/C / tetrahydrofuran; methanol / 3 h / 25 °C / 760 Torr View Scheme
参考文献
Tichenor, Mark S.; Kastrinsky, David B.; Boger, Dale L.
Journal of the American Chemical Society, 2004 , vol. 126, # 27 p. 8396 - 8398
