1: With sodium thiosulfate in methanol; water 3 h; Heating / reflux; 2: With chlorine in methanol; water; acetic acid T=0°C; 1.66667 h; ice/liquid mixture;
参考文献
3-Dimensional Pharmaceuticals, Inc.
Patent: US6350764 B2, 2002 ;
Location in patent: Page column 51-52 ;
