1-乙炔基-4-乙烯基-苯合成路线 （共 9 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 1 h;
参考文献
Malkoch, Michael; Thibault, Raymond J.; Drockenmuller, Eric; Messerschmidt, Martin; Voit, Brigitte; Russell, Thomas P.; Hawker, Craig J.
Journal of the American Chemical Society, 2005 , vol. 127, # 42 p. 14942 - 14949
反应条件
1: 61.8 percent / triethylamine; bis(triphenylphosphine)palladium(II) chloride; copper(II) iodide / 16 h / 50 °C 2: 95.3 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Meng, H.-H. B.; Dalton, L. R.; Wu, S.-T.
Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1994 , vol. 250, p. 303 - 314
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 1.5 h / -10 - 20 °C 1.2: 81 percent / tetrahydrofuran; hexane / -20 - 20 °C 2.1: 88 percent / KOH / ethanol; tetrahydrofuran; H2O / 0 - 20 °C View Scheme
参考文献
Denmark, Scott E.; Neuville, Luc; Christy, Matthew E. L.; Tymonko, Steven A.
Journal of Organic Chemistry, 2006 , vol. 71, # 22 p. 8500 - 8509
反应条件
1.1: triethylamine; Ph3P; Pd(OAc)2 / 2 h / Heating 2.1: n-butyllithium / tetrahydrofuran; hexane / 1.5 h / -10 - 20 °C 2.2: 81 percent / tetrahydrofuran; hexane / -20 - 20 °C 3.1: 88 percent / KOH / ethanol; tetrahydrofuran; H2O / 0 - 20 °C View Scheme
参考文献
Denmark, Scott E.; Neuville, Luc; Christy, Matthew E. L.; Tymonko, Steven A.
Journal of Organic Chemistry, 2006 , vol. 71, # 22 p. 8500 - 8509
反应条件
potassium hydroxide in methanol Heating;
参考文献
Braun,D.; Keppler,H.-G.
Monatshefte fuer Chemie, 1963 , vol. 94, # 6 p. 1250 - 1261
反应条件
1: Al(OiPr)3, iPrOH / 130 - 140 °C 2: (i) aq. KHSO4, Et2O, (ii) (dehydration) 3: Br2 / CHCl3 4: KOH / methanol / Heating View Scheme
参考文献
Braun,D.; Keppler,H.-G.
Monatshefte fuer Chemie, 1963 , vol. 94, # 6 p. 1250 - 1261
反应条件
1: (i) aq. KHSO4, Et2O, (ii) (dehydration) 2: Br2 / CHCl3 3: KOH / methanol / Heating View Scheme
参考文献
Braun,D.; Keppler,H.-G.
Monatshefte fuer Chemie, 1963 , vol. 94, # 6 p. 1250 - 1261
反应条件
1: AlCl3 / CS2 2: Al(OiPr)3, iPrOH / 130 - 140 °C 3: (i) aq. KHSO4, Et2O, (ii) (dehydration) 4: Br2 / CHCl3 5: KOH / methanol / Heating View Scheme
参考文献
Braun,D.; Keppler,H.-G.
Monatshefte fuer Chemie, 1963 , vol. 94, # 6 p. 1250 - 1261
反应条件
iron(III) sulphate hydrate; acetic acid
T=95°C; 24 h; Schlenk technique; regioselective reaction;
参考文献
Bassetti, Mauro; Ciceri, Samuele; Lancia, Federico; Pasquini, Chiara
Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1608 - 1612
