4-氨基-N-(6-氨基-2,4-二氧代-1,3-二丙基-1,2,3,4-四氢-5-嘧啶基)苯甲酰胺合成路线 （共 3 条）
反应条件
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in methanol T=20°C; 5 h;
参考文献
Baraldi, Pier Giovanni; Tabrizi, Mojgan Aghazadeh; Preti, Delia; Bovero, Andrea; Romagnoli, Romeo; Fruttarolo, Francesca; Zaid, Naser Abdel; Moorman, Allan R.; Varani, Katia; Gessi, Stefania; Merighi, Stefania; Borea, Pier Andrea
Journal of Medicinal Chemistry, 2004 , vol. 47, # 6 p. 1434 - 1447
反应条件
1: Na2S2O4; aq. NH3 2: EDAC / methanol / 5 h / 20 °C View Scheme
参考文献
Baraldi, Pier Giovanni; Tabrizi, Mojgan Aghazadeh; Preti, Delia; Bovero, Andrea; Romagnoli, Romeo; Fruttarolo, Francesca; Zaid, Naser Abdel; Moorman, Allan R.; Varani, Katia; Gessi, Stefania; Merighi, Stefania; Borea, Pier Andrea
Journal of Medicinal Chemistry, 2004 , vol. 47, # 6 p. 1434 - 1447
反应条件
sodium hydroxide in methanol T=70 - 80°C; 12 h;
参考文献
Baraldi, Pier Giovanni; Tabrizi, Mojgan Aghazadeh; Preti, Delia; Bovero, Andrea; Romagnoli, Romeo; Fruttarolo, Francesca; Zaid, Naser Abdel; Moorman, Allan R.; Varani, Katia; Gessi, Stefania; Merighi, Stefania; Borea, Pier Andrea
Journal of Medicinal Chemistry, 2004 , vol. 47, # 6 p. 1434 - 1447
