1H-1,2,4-噻唑-1-胺合成路线 (共 4 条)
反应条件
potassium hydroxide; hydroxylamine-o-sulphonic acid in tetrahydrofuran; diethyl ether; ethanol; hexane; di-isopropyl ether; water
参考文献
Dae Woong Pharmaceutical Co., Ltd.
Patent: US5336673 A1, 1994 ;
反应条件
potassium hydroxide; hydroxylamine-o-sulphonic acid in water T=70°C; 1 h;
参考文献
Mendoza, Javier de; Castellanos, Maria Luisa; Fayet, Jean-Pierre; Vertut, Marie Claire; Elguero, Jose
Journal of Chemical Research, Miniprint, 1980 , # 2 p. 514 - 529
反应条件
Amberlite IRA-410 in water 0.166667 h; Ambient temperature; Yield given;
参考文献
Laus; Klotzer
Synthesis, 1989 , # 4 p. 269 - 272
反应条件
NOBF4 in acetonitrile
T=25°C;
参考文献
Abramovitch; Beckert; Gibson Jr.; Belcher; Hundt; Sierra; Olivella; Pennington; Sole
Journal of Organic Chemistry, 2001 , vol. 66, # 4 p. 1242 - 1251