5-溴-2-甲氧基苯甲醛合成路线 （共 49 条）
反应条件
sodium periodate; hydrogen cation; lithium bromide Heating;
参考文献
Journal of Organic Chemistry, , vol. 71, # 13 p. 5043 - 5046
反应条件
potassium carbonate 15 h; Heating;
参考文献
Tetrahedron Letters, , vol. 39, # 15 p. 2055 - 2058
反应条件
copper(II) nitrate; acetic acid
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 205, p. 146
反应条件
3,4,5,6-tetramethyl-t-Bu-X-Phos; potassium hydroxide; tris-(dibenzylideneacetone)dipalladium(0) in 1,4-dioxane; water T=80°C; 18 h;
参考文献
Anderson, Kevin W.; Ikawa, Takashi; Tundel, Rachel E.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2006 , vol. 128, # 33 p. 10694 - 10695
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane T=20°C; 48 h;
参考文献
LaVoie, Edmond J.; Liu, Leroy Fong; Yu, Younong
Patent: US2003/100560 A1, 2003 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in DMF (N,N-dimethyl-formamide) T=20°C; 3 h;
参考文献
Assens, Jean-Louis; Bernhart, Claude; Cabanel-Haudricourt, Frederique; Nisato, Dino
Patent: US2004/10011 A1, 2004 ;
Location in patent: Page/Page column 26 ;
反应条件
in N,N-dimethyl-formamide Heating;
参考文献
Laali, Kenneth K.; Koser, Gerald F.; Subramanyam, Sundar; Forsyth, David A.
Journal of Organic Chemistry, 1993 , vol. 58, # 6 p. 1385 - 1392
反应条件
1.1: 3-chloroperoxybenzoic acid / CH2Cl2 / 72 h / 0 - 20 °C 1.2: 92 percent / 2 M NaOH / diethyl ether 2.1: 69 percent / K2CO3 / dimethylformamide / 2.5 h / 60 °C View Scheme
参考文献
Van der Mey; Hatzelmann; Van Klink; Van der Laan; Sterk; Thibaut; Ulrich; Timmerman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2523 - 2535
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water Suzuki Coupling; 2.16667 h; Heating / reflux;
参考文献
ATHEROGENICS, INC.
Patent: WO2006/4903 A2, 2006 ;
Location in patent: Page/Page column 79-80 ;
反应条件
1.1: 3-chloroperoxybenzoic acid / CH2Cl2 / 72 h / 0 - 20 °C 1.2: 92 percent / 2 M NaOH / diethyl ether 2.1: 69 percent / K2CO3 / dimethylformamide / 2.5 h / 60 °C 3.1: KOtBu / tetrahydrofuran / 2 h 3.2: tetrahydrofuran / 1 h View Scheme
参考文献
Van der Mey; Hatzelmann; Van Klink; Van der Laan; Sterk; Thibaut; Ulrich; Timmerman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2523 - 2535
