2-甲氧基-5-硝基苯甲醛合成路线 （共 16 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 12 h;
参考文献
The Regents of the University of Colorado, a body corporate; Zhang, Wei; Kuthanapillil, Jyothish; Wang, Qi
Patent: US2013/261295 A1, 2013 ;
Location in patent: Paragraph 0166; 0167 ;
反应条件
titanium tetrachloride in hexane; dichloromethane
反应条件
lithium boron tetrafluoride in acetonitrile 4.25 h; Ambient temperature;
参考文献
Lipshutz, Bruce H.; Harvey, Daniel F.
Synthetic Communications, 1982 , vol. 12, # 4 p. 267 - 278
反应条件
sulfuric acid; nitric acid 4 - 13 deg C;
参考文献
Laali, Kenneth K.; Koser, Gerald F.; Subramanyam, Sundar; Forsyth, David A.
Journal of Organic Chemistry, 1993 , vol. 58, # 6 p. 1385 - 1392
反应条件
ammonium cerium(IV) nitrate; trifluoroacetic acid T=23°C; 1 h; Yields of byproduct given;
参考文献
Canadian Journal of Chemistry, , vol. 66, p. 1670 - 1674
反应条件
16 h; Heating / reflux;
参考文献
Pfizer Inc.
Patent: US6369074 B1, 2002 ;
Location in patent: Example 19 ;
US 6369074 B1
参考文献
Current Science, , vol. 4, p. 26
反应条件
(i) hexamethylenetetramine, (ii) aq. AcOH; Multistep reaction;
参考文献
Bulletin de la Societe Chimique de France, , p. 2445 - 2449
反应条件
1: sodium tetrahydroborate / methanol / 1 h / 0 - 5 °C / Inert atmosphere 2: phosphorus tribromide / toluene / 0.5 h / 40 - 100 °C / Inert atmosphere View Scheme
参考文献
Reddy, M. V. Ramana; Venkatapuram, Padmavathi; Mallireddigari, Muralidhar R.; Pallela, Venkat R.; Cosenza, Stephen C.; Robell, Kimberly A.; Akula, Balaiah; Hoffman, Benjamin S.; Reddy, E. Premkumar
Journal of Medicinal Chemistry, 2011 , vol. 54, # 18 p. 6254 - 6276
反应条件
(i) HC(OEt)3, H3PO4, (ii) /BRN= 605351/, ZnCl2, AcOEt, (iii) aq. NaOAc, AcOH; Multistep reaction;
参考文献
Billman; Tonnis
Journal of pharmaceutical sciences, 1971 , vol. 60, # 8 p. 1188 - 1192
