4-(N,n-二苯基氨基)苄醇合成路线 （共 6 条）
反应条件
sodium tetrahydroborate; ethanol T=78°C; 3 h;
参考文献
DOW ADVANCED DISPLAY MATERIALS,LTD.; LEE, Hyo Jung; CHO, Young Jun; KWON, Hyuck Joo; KIM, Bong Ok; KIM, Sung Min; YOON, Seung Soo
Patent: WO2010/126233 A1, 2010 ;
Location in patent: Page/Page column 15 ;
反应条件
1.1: trichlorophosphate / 10 °C / Inert atmosphere 1.2: 24 h / 35 °C / Inert atmosphere 1.3: Cooling with ice; Inert atmosphere 2.1: sodium tetrahydroborate / ethanol; dichloromethane / 2 h / 20 °C / Inert atmosphere View Scheme
参考文献
Dubinina, Galyna G.; Price, Randi S.; Abboud, Khalil A.; Wicks, Geoffrey; Wnuk, Pawel; Stepanenko, Yuriy; Drobizhev, Mikhail; Rebane, Aleksander; Schanze, Kirk S.
Journal of the American Chemical Society, 2012 , vol. 134, # 47 p. 19346 - 19349
反应条件
1.1: copper(I) oxide; sodium t-butanolate / N-methyl-pyrrolidine / 24 h / 90 °C / Inert atmosphere 2.1: trichlorophosphate / 10 °C / Inert atmosphere 2.2: 24 h / 35 °C / Inert atmosphere 2.3: Cooling with ice; Inert atmosphere 3.1: sodium tetrahydroborate / ethanol; dichloromethane / 2 h / 20 °C / Inert atmosphere View Scheme
参考文献
McNulty, James; McLeod, David
Tetrahedron Letters, 2011 , vol. 52, # 42 p. 5467 - 5470
反应条件
1.1: copper(I) oxide; sodium t-butanolate / N-methyl-pyrrolidine / 24 h / 90 °C / Inert atmosphere 2.1: trichlorophosphate / 10 °C / Inert atmosphere 2.2: 24 h / 35 °C / Inert atmosphere 2.3: Cooling with ice; Inert atmosphere 3.1: sodium tetrahydroborate / ethanol; dichloromethane / 2 h / 20 °C / Inert atmosphere View Scheme
参考文献
McNulty, James; McLeod, David
Tetrahedron Letters, 2011 , vol. 52, # 42 p. 5467 - 5470
反应条件
1: With n-hexylMgCl; FeBr2; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=20°C; 0.0833333 h; Inert atmosphere; 2: in di-isopropyl ether; toluene T=120°C; 24 h; Inert atmosphere;
参考文献
Yu, Da-Gang; Wang, Xin; Zhu, Ru-Yi; Luo, Shuang; Zhang, Xiao-Bo; Wang, Bi-Qin; Wang, Lei; Shi, Zhang-Jie
Journal of the American Chemical Society, 2012 , vol. 134, # 36 p. 14638 - 14641
反应条件
1.1: phosphorus tribromide / diethyl ether / 15 h / 0 - 20 °C
2.1: toluene / 24 h / |Reflux
3.1: potassium tert-butylate / tetrahydrofuran / 3.67 h / |Inert atmosphere; |Reflux
3.2: 15 h / 0 - 20 °C / |Inert atmosphere
4.1: sodium hydroxide; sodium tetrahydroborate / tetrahydrofuran; methanol; water / 15 h / 20 °C
View Scheme
参考文献
Dubinina, Galyna G.; Price, Randi S.; Abboud, Khalil A.; Wicks, Geoffrey; Wnuk, Pawel; Stepanenko, Yuriy; Drobizhev, Mikhail; Rebane, Aleksander; Schanze, Kirk S.
Journal of the American Chemical Society, 2012 , vol. 134, # 47 p. 19346 - 19349
