3-(2-氯乙基)-2-噁唑烷酮合成路线 （共 6 条）
反应条件
pyridine; thionyl chloride in benzene T=30°C; 6 h;
参考文献
Vani; Chida; Srinivasan; Chandrasekharam; Singh
Synthetic Communications, 2001 , vol. 31, # 13 p. 2043 - 2046
反应条件
1: oxazolidin-2-one With sodium hydride in DMF (N,N-dimethyl-formamide) T=0 - 20°C; 1 h; 2: 1-bromo-2-chloro-ethane in DMF (N,N-dimethyl-formamide) T=20°C; 72 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1479684 A1, 2004 ;
Location in patent: Page 48 ;
反应条件
triethylamine in benzene
参考文献
Culbertson,B.M.; Dietz,S.
Canadian Journal of Chemistry, 1968 , vol. 46, p. 3399 - 3402
反应条件
ethanol; sodium ethanolate
参考文献
BASF
Patent: DE972304 , 1955 ;
反应条件
1: thionyl chloride 2: sodium ethylate; ethanol View Scheme
参考文献
Delaby et al.
Annales Pharmaceutiques Francaises, 1955 , vol. 13, p. 565,566
反应条件
1: KI, K2CO3 / toluene / Heating
2: H2 / Pd-C / methanol / 16 h / 50 °C
3: CHCl3 / 42 h / Heating
View Scheme
参考文献
Aschwanden; Kyburz; Schoenholzer
Helvetica Chimica Acta, 1976 , vol. 59, # 4 p. 1245 - 1252
