2-碘-1,3,5-三甲氧基苯合成路线 （共 19 条）
反应条件
copper T=240°C; Ullmann coupling; 6 h;
参考文献
Sawada; Aono; Asakawa; Ito; Awano
Journal of Antibiotics, 2000 , vol. 53, # 9 p. 959 - 966
反应条件
1: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane T=80°C; 18 h; 2: 2-iodo-1,3,5-trimethoxy benzene; 4,4,5,5-tetramethyl-[1,3,2]dioxaborolane in 1,4-dioxane T=80°C; 18 h;
参考文献
Commonwealth Scientific and Industrial Research Organisation
Patent: US6680401 B1, 2004 ;
Location in patent: Page column 55 ;
反应条件
1.1: n-butyllithium; zinc dibromide / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 24 h / 80 °C / 8791.75 Torr / Pressure reactor 2.1: methanol; boron tribromide / dichloromethane / 0.02 h / -78 °C / Inert atmosphere 3.1: caesium carbonate / acetone / 0.17 h / 20 °C View Scheme
参考文献
O'Keefe, B. Michael; Simmons, Nicholas; Martin, Stephen F.
Tetrahedron, 2011 , vol. 67, # 24 p. 4344 - 4351
反应条件
CuF2; 1,10-phenanthroline; oxygen; lithium carbonate in dimethyl sulfoxide T=150°C; 36 h; Sealed tube;
参考文献
Zheng, Kui; Liu, Bin; Chen, Shuyou; Chen, Fan
Tetrahedron Letters, 2013 , vol. 54, # 38 p. 5250 - 5252
反应条件
copper(I) oxide in N,N-dimethyl-formamide T=130°C; 12 h;
参考文献
Wen, Qiaodong; Jin, Jisong; Mei, Yuncai; Lu, Ping; Wang, Yanguang
European Journal of Organic Chemistry, 2013 , # 19 p. 4032 - 4036
反应条件
N,N,N',N,-tetramethylethylenediamine; copper diacetate; ammonium hydrogen carbonate T=150°C; 22 h; sealed tube;
参考文献
Zhang, Guoying; Ren, Xinyi; Chen, Jianbin; Hu, Maolin; Cheng, Jiang
Organic Letters, 2011 , vol. 13, # 19 p. 5004 - 5007
反应条件
copper diacetate; silver(l) oxide in 1-methyl-pyrrolidin-2-one T=120°C; 20 h;
参考文献
Zheng, Kui; Yu, Peng; Chen, Shuyou; Chen, Fen; Cheng, Jiang
Chinese Journal of Chemistry, 2013 , vol. 31, # 4 p. 449 - 452
反应条件
formic acid; sodium formate; palladium dichloride in water; dimethyl sulfoxide T=100°C; 36 h;
参考文献
Zhang, Guo-Ying; Yu, Jin-Tao; Hu, Mao-Lin; Cheng, Jiang
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2710 - 2714
反应条件
Cu(NO3)2*3H2O; oxygen; silver carbonate in N,N-dimethyl-formamide T=150°C; 24 h; Schlenk technique;
参考文献
Pawar, Amit B.; Chang, Sukbok
Chemical Communications, 2014 , vol. 50, # 4 p. 448 - 450
反应条件
sodium periodate; sulfuric acid; dihydrogen peroxide in ethanol; water
T=50°C; 0.5 h;
参考文献
Sathiyapriya
Asian Journal of Chemistry, 2011 , vol. 23, # 1 p. 41 - 43
