N-(2-氰基苯基)乙酰胺合成路线 （共 31 条）
反应条件
hydrazine hydrate 1.) abs. ethanol, reflux, overnight; 2.) 100 deg C, 5 h;
参考文献
Canadian Journal of Chemistry, , vol. 62, # 11 p. 2570 - 2577
反应条件
phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water T=180°C; 0.416667 h;
参考文献
Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468
反应条件
phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water T=180°C; 0.666667 h;
参考文献
Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide T=100°C; 48 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=20°C; 3: With hydrogenchloride; water in ethyl acetate
参考文献
Inotek Pharmaceutical, Corp.
Patent: US2006/19980 A1, 2006 ;
Location in patent: Page/Page column 56-57 ;
反应条件
phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water T=180°C; 0.5 h;
参考文献
Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468
反应条件
phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water T=180°C; 0.583333 h;
参考文献
Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468
反应条件
hydrogen; palladium on activated charcoal P=2280 Torr; 24 h;
参考文献
Beddoes, Roy L.; Edwards, W. D.; Joule, J. A.; Mills, O. S.; Street, J. D.
Tetrahedron, 1987 , vol. 43, # 8 p. 1903 - 1920
反应条件
phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water
T=180°C; 0.333333 h;
参考文献
Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468
反应条件
phosphorus pentoxide; N,N-dimethylcyclohexylamine hydrochloride in water
T=180°C; 0.333333 h;
参考文献
Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468
参考文献
Breukink et al.
Recueil des Travaux Chimiques des Pays-Bas, 1957 , vol. 76, p. 401,406
