2,2,-二甲基-2H-苯并吡喃合成路线 （共 66 条）
反应条件
1: 1.) n-butyllithium / 1.) ether, hexane, room temp., 2 h; 2.) -20 deg C, 1 h
2: p-toluenesulfonic acid / toluene / 1 h / 60 °C
View Scheme
参考文献
Talley, John J.
Synthesis, 1983 , # 10 p. 845 - 847
反应条件
1: 1.) n-butyllithium / 1.) ether, hexane, room temp., 2 h; 2.) -20 deg C, 1 h
2: p-toluenesulfonic acid / toluene / 1 h / 60 °C
View Scheme
参考文献
Talley, John J.
Synthesis, 1983 , # 10 p. 845 - 847
反应条件
1: potassium carbonate / 1,4-dioxane / 72 h / Reflux
2: palladium diacetate / cyclohexane / 24 h / 140 °C / Molecular sieve; air
View Scheme
参考文献
Modak, Atanu; Deb, Arghya; Patra, Tuhin; Rana, Sujoy; Maity, Soham; Maiti, Debabrata
Chemical Communications, 2012 , vol. 48, # 35 p. 4253 - 4255
反应条件
Ambient temperaturemacroelectrolysis: mercury pool working electrode, tetraethylammonium p-toluenesulfonate supporting electrolyte;
参考文献
Tsukayama, Masao
Heterocycles, 1997 , vol. 45, # 6 p. 1131 - 1142
反应条件
toluene-4-sulfonic acid in toluene
1 h; Heating;
参考文献
Prado, Soizic; Janin, Yves L.; Bost, Pierre-Etienne
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1605 - 1608
反应条件
1: 70 percent / diethyl ether; tetrahydrofuran / 1 h / 0 °C
2: 2.) H2O / 1.) hexane, ether, RT, 1 h
View Scheme
参考文献
Alberola, Angel; Calvo, Blanca; Gonzalez-Ortega, Alfonso; Lopez, Cristina; Villafane, Fernando
Heterocycles, 1994 , vol. 38, # 4 p. 819 - 832
反应条件
1: K2CO3 / acetone / 70 °C
2: 75 percent / TsOH*H2O / toluene / Heating
3: 5percent aq. NaOH / methanol / 50 °C
4: DDQ / benzene / 80 °C
View Scheme
参考文献
Tsukayama, Masao; Kikuchi, Makoto; Kawamura, Yasuhiko
Heterocycles, 1994 , vol. 38, # 7 p. 1487 - 1490
反应条件
1: 5percent aq. NaOH / methanol / 50 °C
2: DDQ / benzene / 80 °C
View Scheme
参考文献
Tsukayama, Masao; Kikuchi, Makoto; Kawamura, Yasuhiko
Heterocycles, 1994 , vol. 38, # 7 p. 1487 - 1490
反应条件
RhCl3 hydrate; 1,3-bis-(diphenylphosphino)propane in diethylene glycol dimethyl ether
16 h; Inert atmosphereReflux;
参考文献
Broehmer, Manuel C.; Volz, Nicole; Braese, Stefan
Synlett, 2009 , # 9 p. 1383 - 1386
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=130°C; 16 h;
参考文献
Kawase, Yoshiyuki; Yamaguchi, Seiji; Horita, Hisanori; Takeno, Junko; Kameyama, Hideaki
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 4 p. 1153 - 1155
