(S)-2-吡咯烷-2-基噻唑-4-甲酸乙酯合成路线 (共 3 条)
反应条件
trifluoroacetic acid in methoxybenzene T=0°C; Decarboxylation; hydrolysis;
参考文献
Stanchev, Mincho; Tabakova, Svoboda; Videnov, Georgi; Golovinsky, Evgeny; Jung, Guenther
Archiv der Pharmazie, 1999 , vol. 332, # 9 p. 297 - 304
反应条件
1: KHCO3 / 1,2-dimethoxy-ethane / 0.02 h 2: trifluoroacetic anhydride; pyridine / 1,2-dimethoxy-ethane / 0 - 20 °C 3: 96 percent / TFA / methoxybenzene / 0 °C View Scheme
参考文献
Archiv der Pharmazie, , vol. 332, # 9 p. 297 - 304
反应条件
1: KHCO3 / 1,2-dimethoxy-ethane / 0.02 h 2: trifluoroacetic anhydride; pyridine / 1,2-dimethoxy-ethane / 0 - 20 °C 3: 96 percent / TFA / methoxybenzene / 0 °C View Scheme
参考文献
Archiv der Pharmazie, , vol. 332, # 9 p. 297 - 304