2-氯-5-硝基苯甲酸合成路线 （共 155 条）
参考文献
Journal of the Chemical Society, , p. 102,107
Chemische Berichte, , vol. 64, p. 2381,2384
反应条件
1: With hydrazine hydrate in ethanol 16 h; Reflux; 2: With hydrogenchloride in water 8 h; Reflux;
参考文献
GLAXOSMITHKLINE LLC; QIN, Donghui; CHEUNG, Mui; JOSHI, Hemant; TANGIRALA, Raghuram; BETHI, Sridhar, Reddy
Patent: WO2012/162129 A1, 2012 ;
Location in patent: Page/Page column 40-41 ;
WO 2012/162129 A1
反应条件
1: in methanol 12 h; Heating / reflux; 2: With hydrogenchloride in water T=20°C; pH=~ 2; 0.5 h;
参考文献
F2G LTD
Patent: WO2006/123145 A1, 2006 ;
Location in patent: Page/Page column 61-62 ;
反应条件
1.1: methanol / 15 h / |Reflux 2.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 80 °C 2.2: 80 °C View Scheme
参考文献
Lori, Franco; Chafouleas, James; De Forni, Davide; Solinas, Antonio; Varga, Zoltán; Greff, Zoltán; Örfi, László; Kéri, György
Patent: US2014/57911 A1, 2014 ;
反应条件
1: 93.1 percent / phosphorus pentachloride / benzene / 3 h / Heating 2: 85.4 percent / aluminium chloride / 1 h / Heating View Scheme
参考文献
Parlow, John J.; Mischke, Deborah A.; Woodard, Scott S.
Journal of Organic Chemistry, 1997 , vol. 62, # 17 p. 5908 - 5919
反应条件
phosphorus pentachloride man fuegt AlCl3 hinzu und zersetzt mit Eis;
参考文献
Ullmann; Ernst
Chemische Berichte, 1906 , vol. 39, p. 300
反应条件
1: tin; hydrochloric acid 2: hydrochloric acid / Diazotization View Scheme
参考文献
Huebner
Justus Liebigs Annalen der Chemie, 1884 , vol. 222, p. 198
反应条件
copper; potassium carbonate in N,N-dimethyl-formamide T=25°C; Ullmann condensation; 0.25 h; ultrasonic irradiation;
参考文献
Docampo, Maite L.; Pellon, Rolando F.; Estevez-Braun, Ana; Ravelo, Angel G.
European Journal of Organic Chemistry, 2007 , # 24 p. 4111 - 4115
反应条件
1: hydrogenchloride / water; 1,4-dioxane / 3 h 2: SnCl2·2H2O; ethanol / 2 h / |Sealed tube; |Sonication View Scheme
参考文献
FLYNN, Gary, A.
Patent: WO2013/22766 A1, 2013 ;
WO 2013/022766 A1
