5-(吡啶-3-基)-1H-吡唑-3-甲酸乙酯合成路线 （共 5 条）
反应条件
hydrazine hydrate in ethanol 4 h; Reflux;
参考文献
Bischoff, Alexander; Subramanya, Hosahalli; Sundaresan, Kumar; Sammeta, Srinivasa Raju; Vaka, Anil Kumar
Patent: US2010/160323 A1, 2010 ;
Location in patent: Page/Page column 36 ;
US 20100160323 A1
反应条件
1: 84 percent / EtONa / 13 h / 78 °C 2: 83 percent / NH2NH2*H2O; AcOH / 7 h / 105 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 11 p. 1211 - 1214
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; Reduction; 5 h;
参考文献
Chang, Kwan Young; Kim, Sung Hoon; Nam, Ghilsoo; Seo, Jae Hong; Kim, Joong Hyup; Ha, Deok-Chan
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 11 p. 1211 - 1214
参考文献
Clemo; Holmes
Journal of the Chemical Society, 1934 , p. 1739
反应条件
ammonium hydroxide
T=20°C; ammonolysis; 35 h;
参考文献
Chang, Kwan Young; Kim, Sung Hoon; Nam, Ghilsoo; Seo, Jae Hong; Kim, Joong Hyup; Ha, Deok-Chan
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 11 p. 1211 - 1214
