1: 2,5-dimethylstyrene With (C5H3N)(MeC=N(C6H4-2,6-iPr2))2; iron(II) chloride; c-PentMgBr in tetrahydrofuran; diethyl ether T=20°C; 2 h; Inert atmosphere; 2: carbon dioxide in tetrahydrofuran; diethyl ether 0.5 h; Inert atmosphere; regioselective reaction;

aluminium trichloride T=100°C;

1.1: potassium carbonate / 1,4-dioxane / 16 h / Reflux 2.1: (C5H3N)(MeC=N(C6H4-2,6-iPr2))2; iron(II) chloride; c-PentMgBr / tetrahydrofuran; diethyl ether / 2 h / 20 °C / Inert atmosphere 2.2: 0.5 h / Inert atmosphere View Scheme

xylene Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge und Erhitzen der erhaltenen <2.5-Dimethyl-benzyl>-malonsaeure;

暂无反应条件数据

2: (reduction) 3: TsOH / benzene / Heating View Scheme

1: benzene; thionyl chloride 2: AlCl3; petroleum ether 3: amalgamated zinc; aqueous HCl View Scheme