3-(3,4-二甲基苯基)丙酸合成路线 （共 14 条）
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol T=120°C; P=75005.9 Torr; 20 h;
参考文献
Bartmann; Konz; Ruger
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 3 p. 677 - 682
反应条件
potassium hydroxide; sulfuric acid in diethyl ether; ethanol; water
参考文献
Korea Research Institute of Chemical Technology
Patent: EP721939 A1, 1996 ;
反应条件
potassium hydroxide; sulfuric acid in diethyl ether; ethanol; water
参考文献
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Patent: EP525360 A2, 1993 ;
反应条件
hydrogen; palladium in tetrahydrofuran; ethanol
反应条件
1: 82.4 percent / pyridine / 6 h / Heating 2: 99 percent / ethanolic HCl, H2 / 10percent Pd on charcoal / ethanol / 20 h / 120 °C / 75005.9 Torr View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, # 3 p. 677 - 682
反应条件
1: 83 percent / PCC / CH2Cl2 / 2 h / Ambient temperature 2: 92.2 percent / pyridine, piperidine / 48 h / 80 °C 3: 98.2 percent / H2 / 10percent Pd/C / dioxane / 517.1 - 1551.4 Torr View Scheme
参考文献
Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
反应条件
1: 99 percent / LiAlH4 / diethyl ether / 1.) reflux, 3 h, 2.) room temp., overnight 2: 83 percent / PCC / CH2Cl2 / 2 h / Ambient temperature 3: 92.2 percent / pyridine, piperidine / 48 h / 80 °C 4: 98.2 percent / H2 / 10percent Pd/C / dioxane / 517.1 - 1551.4 Torr View Scheme
参考文献
Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
反应条件
1: 92.4 percent / conc. H2SO4 / 48 h / Heating 2: 99 percent / LiAlH4 / diethyl ether / 1.) reflux, 3 h, 2.) room temp., overnight 3: 83 percent / PCC / CH2Cl2 / 2 h / Ambient temperature 4: 92.2 percent / pyridine, piperidine / 48 h / 80 °C 5: 98.2 percent / H2 / 10percent Pd/C / dioxane / 517.1 - 1551.4 Torr View Scheme
参考文献
Monatshefte fur Chemie, , vol. 127, # 2 p. 185 - 200
参考文献
BP Corporation North America Inc.
Patent: EP1157047 B1, 2003 ;
反应条件
phosphoric acid; phosphorus pentoxide T=90°C; 3 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, # 3 p. 677 - 682
