6-羟基异喹啉-1(2H)-酮合成路线 （共 10 条）
反应条件
hydrogenchloride; water T=180°C; 0.666667 h; Microwave irradiation;
参考文献
N.V. Organon
Patent: US2008/45566 A1, 2008 ;
Location in patent: Page/Page column 8 ;
反应条件
boron tribromide in dichloromethane T=0 - 20°C; 18 h;
参考文献
US2010/56566 A1, ;
Page/Page column 25 ;
反应条件
1: diphenylphosphoranyl azide; triethylamine / toluene 2: bis-maleimidodiphenyl-methane acid / 250 °C 3: boron tribromide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1084 - 1088
反应条件
1: sodium hydroxide 2: diphenylphosphoranyl azide; triethylamine / toluene 3: bis-maleimidodiphenyl-methane acid / 250 °C 4: boron tribromide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1084 - 1088
反应条件
1: toluene 2: sodium hydroxide 3: diphenylphosphoranyl azide; triethylamine / toluene 4: bis-maleimidodiphenyl-methane acid / 250 °C 5: boron tribromide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1084 - 1088
反应条件
hydrogen iodide Hydrolysis; dehydration; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 23 p. 4875 - 4889
反应条件
1: NaOMe; butyl nitrite 2: aq. HI / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 23 p. 4875 - 4889
反应条件
1: bis-maleimidodiphenyl-methane acid / 250 °C 2: boron tribromide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1084 - 1088
参考文献
Chemische Berichte, , vol. 37, p. 1976
参考文献
Kusel
Chemische Berichte, 1904 , vol. 37, p. 1976
